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Key Features
- Provides a systematic overview of the field, from fundamentals, to current challenges and opportunities
- Encompasses the classic paradigm of tissue engineering for creation of new functional tissue
- Discusses enabling technologies such as bioprinting, organ-on-chip systems and in silico simulations
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About the Book
Biomaterials for Organ and Tissue Regeneration: New Technologies and Future Prospects examines the use of biomaterials in applications related to artificial tissues and organs. With a strong focus on fundamental and traditional tissue engineering strategies, the book also examines how emerging and enabling technologies are being developed and applied. Sections provide essential information on biomaterial, cell properties and cell types used in organ generation. A section on state-of-the-art in organ regeneration for clinical purposes is followed by a discussion on enabling technologies, such as bioprinting, on chip organ systems and in silico simulations.
Readership Biomaterials/Biomedical Engineering/Tissue Engineering researchers; medical researchers in transplant surgery, cardiology, vascular surgery, and related areas; graduate students in biomedical engineering and medicine for courses such as biomaterials, tissue engineering, and regenerative medicine
Content 1. Introduction
Section 1: Biomaterials 2. Classes of Biomaterials used in Tissue/Organ Regeneration 3. Physicochemical Properties of Biomaterials 4. Synthesis or Modification of Biomaterials for Regenerative Medicine Applications 5. Surface Modifications of Biomaterials for Tissue Engineering
Section 2: Cell microenvironment and signalling 6. Cell microenvironment and ECM 7. Cell signalling and strategies to modulate cell behaviour
Section 3: Cells 8. Stem cells: sources, properties and cell types 9. Tissue specific cells: sources, properties and cell types 10. Cell differentiation: sources, properties and cell types 11. Immune cells: sources, properties and cell types 12. Angiogenesis/vascular cells: sources, properties and cell types
Section 4: Organ specific Artificial tissues/Organs 13. Heart/Cardiovascular tissues 14. Respiratory system tissues 15. Digestive system tissues 16. Kidney Tissue Engineering 17. Liver Tissue Engineering 18. Pancreas Tissue Engineering 19. Neural Tissue Engineering 20. Musculoskeletal Tissue engineering
Section 5: Biotechnological approaches and Enabling technologies related to organ regeneration 21. Emerging biotechnological approaches with respect to organ regeneration: SiRNA, miRNA, CRISPR, CAR-T therapy, -omics approaches etc. 22. Bioreactors 23. On-chip organ systems 24. In vitro disease and organ models 25. Bioprinting 26. Biorobotics 27. Imaging techniques for biomaterials, stem cells and engineered tissues/organs 28. Future perspectives/Industrialisation and Up-scaling of organ regeneration technologies
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